13

Retrieve all proteins belongong to the Hierarchical Orthologous Group (HOG) at the level 'Vertebrata' to which humans' CDIN1 gene belong, together with their gene name symbol if available.

Use at

• https://sparql.omabrowser.org/sparql

PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX orth: <http://purl.org/net/orth#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX up: <http://purl.uniprot.org/core/>

SELECT DISTINCT ?HOG ?MEMBER ?GENE_LABEL
WHERE {
    ?HOG a orth:OrthologsCluster ;
      orth:hasHomologousMember ?node1 ;
      orth:hasTaxonomicRange ?taxRange .
    ?taxRange orth:taxRange 'Vertebrata' .
    ?node1 orth:hasHomologousMember* ?query ;
      orth:hasHomologousMember* ?MEMBER .
    ?MEMBER a orth:Protein .
    OPTIONAL {
        ?MEMBER rdfs:label ?GENE_LABEL .
    }
    ?query a orth:Protein ;
      orth:organism/obo:RO_0002162/up:scientificName 'Homo sapiens';
      rdfs:label 'CDIN1'.
}

graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
  v6("?GENE_LABEL"):::projected 
  v1("?HOG"):::projected 
  v5("?MEMBER"):::projected 
  v2("?node1")
  v4("?query")
  v3("?taxRange")
  a1((" "))
  a2((" "))
  c2(["orth:OrthologsCluster"]):::iri 
  c12(["Homo sapiens"]):::literal 
  c7(["orth:Protein"]):::iri 
  c6(["Vertebrata"]):::literal 
  c13(["CDIN1"]):::literal 
  v1 --"a"-->  c2
  v1 --"orth:hasHomologousMember"-->  v2
  v1 --"orth:hasTaxonomicRange"-->  v3
  v3 --"orth:taxRange"-->  c6
  v2 --"orth:hasHomologousMember"-->  v4
  v2 --"orth:hasHomologousMember"-->  v5
  v5 --"a"-->  c7
  subgraph optional0["(optional)"]
  style optional0 fill:#bbf,stroke-dasharray: 5 5;
    v5 -."rdfs:label".->  v6
  end
  v4 --"a"-->  c7
  v4 --"orth:organism"-->  a1
  a1 --"obo:RO_0002162"-->  a2
  a2 --"up:scientificName"-->  c12
  v4 --"rdfs:label"-->  c13