34

Lipids affected by human enzymes

Use at

• https://sparql.swisslipids.org/sparql/

PREFIX owl: <http://www.w3.org/2002/07/owl#>
PREFIX rh: <http://rdf.rhea-db.org/>
PREFIX taxon: <http://purl.uniprot.org/taxonomy/>
PREFIX up: <http://purl.uniprot.org/core/>

SELECT ?swisslipid  {
  ?swisslipid owl:equivalentClass ?chebi .
  SERVICE <https://sparql.rhea-db.org/sparql> {
    ?rhea rh:side/rh:contains/rh:compound ?compound .
	?compound (rh:chebi|(rh:reactivePart/rh:chebi)|(rh:underlyingChebi/rh:chebi)) ?metabolite . 
  }
  SERVICE <https://sparql.uniprot.org/sparql> {
    ?catalyticActivityAnnotation up:catalyticActivity/up:catalyzedReaction ?rhea .
    ?protein up:annotation ?catalyticActivityAnnotation ;
             up:organism taxon:9606 .
  }
}

graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
  v6("?catalyticActivityAnnotation")
  v2("?chebi")
  v4("?compound")
  v5("?metabolite")
  v7("?protein")
  v3("?rhea")
  v1("?swisslipid"):::projected 
  a1((" "))
  a2((" "))
  a3((" "))
  a4((" "))
  a5((" "))
  c14(["taxon:9606"]):::iri 
  v1 --"owl:equivalentClass"-->  v2
  subgraph s1["https://sparql.rhea-db.org/sparql"]
    style s1 stroke-width:4px;
    v3 --"rh:side"-->  a1
    a1 --"rh:contains"-->  a2
    a2 --"rh:compound"-->  v4
    subgraph union0[" Union "]
    subgraph union0l[" "]
      style union0l fill:#abf,stroke-dasharray: 3 3;
      subgraph union1[" Union "]
      subgraph union1l[" "]
        style union1l fill:#abf,stroke-dasharray: 3 3;
        v4 --"rh:underlyingChebi"-->  a4
        a4 --"rh:chebi"-->  v5
      end
      subgraph union1r[" "]
        style union1r fill:#abf,stroke-dasharray: 3 3;
        v4 --"rh:reactivePart"-->  a3
        a3 --"rh:chebi"-->  v5
      end
      union1r <== or ==> union1l
      end
    end
    subgraph union0r[" "]
      style union0r fill:#abf,stroke-dasharray: 3 3;
      v4 --"rh:chebi"-->  v5
    end
    union0r <== or ==> union0l
    end
  end
  subgraph s2["https://sparql.uniprot.org/sparql"]
    style s2 stroke-width:4px;
    v6 --"up:catalyticActivity"-->  a5
    a5 --"up:catalyzedReaction"-->  v3
    v7 --"up:annotation"-->  v6
    v7 --"up:organism"-->  c14
  end