137_interaction_partners_and_evidence_count

interaction
protein-protein interaction
TP53

Find the interaction partners of human tumor suppressor TP53 (P04637) and the number of experiments supporting each interaction

Use at

https://sparql.uniprot.org/sparql/

PREFIX up: <http://purl.uniprot.org/core/>
PREFIX uniprotkb: <http://purl.uniprot.org/uniprot/>
PREFIX owl: <http://www.w3.org/2002/07/owl#>

SELECT
  DISTINCT
    ?partnerProtein
    ?experiments
WHERE {
  uniprotkb:P04637 up:interaction ?interaction .
  ?interaction a up:Non_Self_Interaction ;
    up:participant ?partner ;
    up:experiments ?experiments .
  # up:participant identifies the interacting molecule by its IntAct
  # identifier; owl:sameAs links that identifier back to the UniProt
  # protein it corresponds to.
  ?partner owl:sameAs ?partnerProtein .
  FILTER(?partnerProtein != uniprotkb:P04637)
}
ORDER BY DESC(?experiments)

graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
  v1("?experiments"):::projected 
  v3("?interaction")
  v4("?partner")
  v2("?partnerProtein"):::projected 
  c4(["up:Non_Self_Interaction"]):::iri 
  c1(["uniprotkb:P04637"]):::iri 
  f0[["?partnerProtein != 'uniprotkb:P04637'"]]
  f0 --> v2
  c1 --"up:interaction"-->  v3
  v3 --"a"-->  c4
  v3 --"up:participant"-->  v4
  v3 --"up:experiments"-->  v1
  v4 --"owl:sameAs"-->  v2