@prefix ex: <https://sparql.uniprot.org/.well-known/sparql-examples/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix schema: <https://schema.org/> .
@prefix sh: <http://www.w3.org/ns/shacl#> .

ex:140_disulfide_bonds_and_interchain_links a sh:SPARQLExecutable,
        sh:SPARQLSelectExecutable ;
    rdfs:comment "Find the disulfide bonds of human insulin (P01308), the pair of residue positions each one connects, and whether it links two different chains (e.g. the A and B chains of mature insulin) rather than two residues within the same chain"@en ;
    sh:prefixes _:sparql_examples_prefixes ;
    sh:select """PREFIX up: <http://purl.uniprot.org/core/>
PREFIX uniprotkb: <http://purl.uniprot.org/uniprot/>
PREFIX faldo: <http://biohackathon.org/resource/faldo#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>

SELECT
  ?annotation
  (GROUP_CONCAT(STR(?position); separator="-") AS ?positions)
  (SAMPLE(?rawComment) AS ?interchainNote)
WHERE {
  uniprotkb:P01308 up:annotation ?annotation .
  ?annotation a up:Disulfide_Bond_Annotation ;
    up:range ?range .
  # Each disulfide bond annotation has one up:range per residue it
  # connects; a plain xsd:int position must be coerced with STR() before
  # GROUP_CONCAT can aggregate it.
  ?range faldo:begin/faldo:position ?position .
  # Absence of a comment means the bond is intra-chain; a comment
  # mentioning "Interchain" means it links two separate chains.
  OPTIONAL { ?annotation rdfs:comment ?rawComment }
}
GROUP BY ?annotation""" ;
    schema:keywords "PTM" , "disulfide bond" , "post-translational modification" ;
    schema:target <https://sparql.uniprot.org/sparql/> .