145_mitochondrial_transit_peptides

transit peptide
mitochondrion
molecule processing

Find reviewed human proteins with a transit peptide targeting them to the mitochondrion, and the extent of that transit peptide

Use at

https://sparql.uniprot.org/sparql/

PREFIX up: <http://purl.uniprot.org/core/>
PREFIX taxon: <http://purl.uniprot.org/taxonomy/>
PREFIX faldo: <http://biohackathon.org/resource/faldo#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>

SELECT
  ?protein
  ?destination
  ?begin
  ?end
WHERE {
  ?protein a up:Protein ;
    up:organism taxon:9606 ;
    up:reviewed true ;
    up:annotation ?annotation .
  ?annotation a up:Transit_Peptide_Annotation ;
    rdfs:comment ?destination ;
    up:range ?range .
  ?range faldo:begin/faldo:position ?begin ;
    faldo:end/faldo:position ?end .
  FILTER(CONTAINS(?destination, "Mitochondrion"))
}

graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
  v3("?annotation")
  v5("?begin"):::projected 
  v1("?destination"):::projected 
  v6("?end"):::projected 
  v2("?protein"):::projected 
  v4("?range")
  a1((" "))
  a2((" "))
  c5(["taxon:9606"]):::iri 
  c7(["true^^xsd:boolean"]):::literal 
  c3(["up:Protein"]):::iri 
  c9(["up:Transit_Peptide_Annotation"]):::iri 
  f0[["contains(?destination,'Mitochondrion')"]]
  f0 --> v1
  v2 --"a"-->  c3
  v2 --"up:organism"-->  c5
  v2 --"up:reviewed"-->  c7
  v2 --"up:annotation"-->  v3
  v3 --"a"-->  c9
  v3 --"rdfs:comment"-->  v1
  v3 --"up:range"-->  v4
  v4 --"faldo:begin"-->  a1
  a1 --"faldo:position"-->  v5
  v4 --"faldo:end"-->  a2
  a2 --"faldo:position"-->  v6