146_propeptide_regions_removed_during_maturation

propeptide
molecule processing

Find propeptide regions of reviewed human proteins that are removed during protein maturation, with their extent

Use at

https://sparql.uniprot.org/sparql/

PREFIX up: <http://purl.uniprot.org/core/>
PREFIX taxon: <http://purl.uniprot.org/taxonomy/>
PREFIX faldo: <http://biohackathon.org/resource/faldo#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>

SELECT ?protein ?description ?begin ?end
WHERE {
  ?protein a up:Protein ;
    up:organism taxon:9606 ;
    up:reviewed true ;
    up:annotation ?annotation .
  ?annotation a up:Propeptide_Annotation ;
    up:range ?range .
  OPTIONAL { ?annotation rdfs:comment ?description }
  ?range faldo:begin/faldo:position ?begin ;
    faldo:end/faldo:position ?end .
}

graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
  v2("?annotation")
  v5("?begin"):::projected 
  v4("?description"):::projected 
  v6("?end"):::projected 
  v1("?protein"):::projected 
  v3("?range")
  a1((" "))
  a2((" "))
  c4(["taxon:9606"]):::iri 
  c8(["up:Propeptide_Annotation"]):::iri 
  c6(["true^^xsd:boolean"]):::literal 
  c2(["up:Protein"]):::iri 
  v1 --"a"-->  c2
  v1 --"up:organism"-->  c4
  v1 --"up:reviewed"-->  c6
  v1 --"up:annotation"-->  v2
  v2 --"a"-->  c8
  v2 --"up:range"-->  v3
  subgraph optional0["(optional)"]
  style optional0 fill:#bbf,stroke-dasharray: 5 5;
    v2 -."rdfs:comment".->  v4
  end
  v3 --"faldo:begin"-->  a1
  a1 --"faldo:position"-->  v5
  v3 --"faldo:end"-->  a2
  a2 --"faldo:position"-->  v6