@prefix ex: <https://sparql.uniprot.org/.well-known/sparql-examples/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix schema: <https://schema.org/> .
@prefix sh: <http://www.w3.org/ns/shacl#> .

ex:147_enzymes_with_kinetic_parameters a sh:SPARQLExecutable,
        sh:SPARQLSelectExecutable ;
    rdfs:comment "Find reviewed enzymes with reported kinetic parameters (Michaelis-Menten constant Km and/or maximal velocity Vmax) and their reported values"@en ;
    sh:prefixes _:sparql_examples_prefixes ;
    sh:select """PREFIX up: <http://purl.uniprot.org/core/>

SELECT ?protein ?km ?vmax
WHERE {
  ?protein a up:Protein ;
    up:reviewed true ;
    up:annotation ?annotation .
  ?annotation a up:Kinetics_Annotation .
  OPTIONAL { ?annotation up:measuredAffinity ?km }
  OPTIONAL { ?annotation up:measuredActivity ?vmax }
}""" ;
    schema:keywords "enzyme" , "kinetics" , "Km" , "Vmax" ;
    schema:target <https://sparql.uniprot.org/sparql/> .