218_protein_amino_acid_composition

amino acid
sequence
composition

Count how many times each of the 20 standard amino acids occurs in human TP53's (P04637) canonical sequence, using STRLEN(sequence) minus STRLEN(sequence with that residue letter removed) as an amino-acid-counting trick rather than a per-position scan. Note: for performance over a larger set rewrite this as a huge union.

Use at

https://sparql.uniprot.org/sparql/

PREFIX up: <http://purl.uniprot.org/core/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>

SELECT
  ?residue
  ?count
WHERE {
  <http://purl.uniprot.org/uniprot/P04637> up:sequence ?sequence .
  ?sequence a up:Simple_Sequence ;
    rdf:value ?seq .
  VALUES ?residue { "A" "R" "N" "D" "C" "Q" "E" "G" "H" "I" "L" "K" "M" "F" "P" "S" "T" "W" "Y" "V" }
  BIND(STRLEN(?seq) - STRLEN(REPLACE(?seq, ?residue, "")) AS ?count)
}
ORDER BY DESC(?count)

graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
  v5("?count"):::projected 
  v4("?residue"):::projected 
  v3("?seq")
  v2("?sequence")
  c4(["up:Simple_Sequence"]):::iri 
  c1([http://purl.uniprot.org/uniprot/P04637]):::iri 
  c1 --"up:sequence"-->  v2
  v2 --"a"-->  c4
  v2 --"rdf:value"-->  v3
  bind0[/VALUES ?residue/]
  bind0-->v4
  bind00(["A"])
  bind00 --> bind0
  bind01(["R"])
  bind01 --> bind0
  bind02(["N"])
  bind02 --> bind0
  bind03(["D"])
  bind03 --> bind0
  bind04(["C"])
  bind04 --> bind0
  bind05(["Q"])
  bind05 --> bind0
  bind06(["E"])
  bind06 --> bind0
  bind07(["G"])
  bind07 --> bind0
  bind08(["H"])
  bind08 --> bind0
  bind09(["I"])
  bind09 --> bind0
  bind010(["L"])
  bind010 --> bind0
  bind011(["K"])
  bind011 --> bind0
  bind012(["M"])
  bind012 --> bind0
  bind013(["F"])
  bind013 --> bind0
  bind014(["P"])
  bind014 --> bind0
  bind015(["S"])
  bind015 --> bind0
  bind016(["T"])
  bind016 --> bind0
  bind017(["W"])
  bind017 --> bind0
  bind018(["Y"])
  bind018 --> bind0
  bind019(["V"])
  bind019 --> bind0
  bind1[/"string-length(?seq) - string-length(replace(?seq,?residue,''))"/]
  v3 --o bind1
  v4 --o bind1
  bind1 --as--o v5