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Select enzymes that have ligands known to have an allosteric effect

Use at

• https://sparql.uniprot.org/sparql/

PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX up: <http://purl.uniprot.org/core/>

SELECT
  ?protein
  ?ligandName 
  ?ligandNote
  ?chebi
WHERE {
   ?protein up:annotation ?annotation .
   ?annotation a up:Binding_Site_Annotation . 
   ?annotation up:ligand ?ligand .
   ?ligand rdfs:comment ?ligandNote ;
     rdfs:subClassOf ?chebi ;
     rdfs:label ?ligandName .
   FILTER(REGEX(?ligandNote, "allosteric", "i"))
}

graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
  v3("?annotation")
  v5("?chebi"):::projected 
  v4("?ligand")
  v6("?ligandName"):::projected 
  v1("?ligandNote"):::projected 
  v2("?protein"):::projected 
  c5(["up:Binding_Site_Annotation"]):::iri 
  f0[["regex(?ligandNote,'allosteric','i')"]]
  f0 --> v1
  v2 --"up:annotation"-->  v3
  v3 --"a"-->  c5
  v3 --"up:ligand"-->  v4
  v4 --"rdfs:comment"-->  v1
  v4 --"rdfs:subClassOf"-->  v5
  v4 --"rdfs:label"-->  v6