neXtProt/NXQ_00218

Proteins for which different splice isoforms have a different subcellular location or function

Use at

• https://sparql.nextprot.org/sparql

PREFIX : <http://nextprot.org/rdf/>
PREFIX nextprot_cv: <http://nextprot.org/rdf/terminology/>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>

#A0A1B0GVQ0,A0AVT1 ,A0PJK1...



SELECT DISTINCT ?entry WHERE {
 ?entry :isoform ?iso1, ?iso2.
 ?iso1 :swissprotDisplayed true .
 ?iso2 :swissprotDisplayed false .
 {
 ?iso2 :function / :term ?functerm .
 filter (?functerm != nextprot_cv:GO_0005515) #protein-binding
 filter not exists {?iso1 :function / :term ?functerm .}
 }
 UNION
 {
 ?iso2 :functionInfo / rdfs:comment ?functext .
 filter not exists {?iso1 :functionInfo / rdfs:comment ?functext .}
 }
 UNION
 {
 ?iso2 :cellularComponent / :term ?locterm .
 filter not exists {?iso1 :cellularComponent / :term ?locterm}
 }
}

graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
  v1("?entry"):::projected 
  v4("?functerm")
  v5("?functext")
  v2("?iso1")
  v3("?iso2")
  v6("?locterm")
  a2((" "))
  a1((" "))
  a4((" "))
  a3((" "))
  a6((" "))
  a5((" "))
  c3(["true^^xsd:boolean"]):::literal 
  c4(["false^^xsd:boolean"]):::literal 
  v1 --":isoform"-->  v2
  v1 --":isoform"-->  v3
  v2 --":swissprotDisplayed"-->  c3
  v3 --":swissprotDisplayed"-->  c4
  subgraph union0[" Union "]
  subgraph union0l[" "]
    style union0l fill:#abf,stroke-dasharray: 3 3;
    subgraph union1[" Union "]
    subgraph union1l[" "]
      style union1l fill:#abf,stroke-dasharray: 3 3;
      f0[["not  "]]
      subgraph f0e0["Exists Clause"]
        e0v1 --":cellularComponent"-->  e0a1
        e0a1 --":term"-->  e0v2
        e0v1("?iso1"):::projected 
        e0v2("?locterm"):::projected 
        e0a1((" ")):::projected 
      end
      f0--EXISTS--> f0e0
      f0 --> v2
      f0 --> c10
      f0 --> a5
      f0 --> c6
      f0 --> v6
      v2 --":cellularComponent"-->  a5
      a5 --":term"-->  v6
      v3 --":cellularComponent"-->  a6
      a6 --":term"-->  v6
    end
    subgraph union1r[" "]
      style union1r fill:#abf,stroke-dasharray: 3 3;
      f1[["not  "]]
      subgraph f1e1["Exists Clause"]
        e1v1 --":functionInfo"-->  e1a1
        e1a1 --"rdfs:comment"-->  e1v2
        e1v2("?functext"):::projected 
        e1v1("?iso1"):::projected 
        e1a1((" ")):::projected 
      end
      f1--EXISTS--> f1e1
      f1 --> v2
      f1 --> c8
      f1 --> a3
      f1 --> c9
      f1 --> v5
      v2 --":functionInfo"-->  a3
      a3 --"rdfs:comment"-->  v5
      v3 --":functionInfo"-->  a4
      a4 --"rdfs:comment"-->  v5
    end
    union1r <== or ==> union1l
    end
  end
  subgraph union0r[" "]
    style union0r fill:#abf,stroke-dasharray: 3 3;
    f2[["not  "]]
    subgraph f2e2["Exists Clause"]
      e2v1 --":function"-->  e2a1
      e2a1 --":term"-->  e2v2
      e2v2("?functerm"):::projected 
      e2v1("?iso1"):::projected 
      e2a1((" ")):::projected 
    end
    f2--EXISTS--> f2e2
    f2 --> v2
    f2 --> c5
    f2 --> a1
    f2 --> c6
    f2 --> v4
    v2 --":function"-->  a1
    a1 --":term"-->  v4
    f3[["?functerm != ':terminology/GO_0005515'"]]
    f3 --> v4
    v3 --":function"-->  a2
    a2 --":term"-->  v4
  end
  union0r <== or ==> union0l
  end